The Board of Regents, The University of Texas System;The Texas A&；M University System
发明人:
Venu G. Varanasi,Azhar Ilyas,Philip Roger Kramer,Taha Azimaie,Pranesh B. Aswath,Tugba Cebe
申请号：
US15360788
公开号：
US10442182B2
申请日:
2016.11.23
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Bio-Inks and methods of using compositions comprising the bio-Inks are disclosed. 3-D tissue repair and regeneration through precise and specific formation of biodegradable tissue scaffolds in a tissue site using the bio-inks are also provided. Specific methylacrylated gelatin hydrogels (MAC) and methacrylated chitosan (MACh) preparations formulated with sucrose, a silicate-containing component (such as laponite), and/or a cross-linking agent (such as a photo-initiator or chemical initiator), as well as powdered preparations of these, are also disclosed. Kits containing these preparations are provided for point-of-care tissue repair in vivo. Superior, more complete (up to 99.85% tissue regeneration within 4 weeks applied in situ), and rapid in situ tissue repair and bone formation are also demonstrated.
