KIM SUNG WUK,JUN SUNG SOO,JO YOUNG GWAN,KOO JA SEONG,SON JAE WOON
申请号：
IN2137/DELNP/2009
公开号：
IN284361B
申请日:
2009.03.31
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
Disclosed herein is a lag time delayed-release combination pharmaceutical composition comprising of an angiotensin-II-receptor blocker and an HMG-CoA reductase inhibitor, as well as a preparation method thereof. The composition is designed based on chronotherapy in which active ingredients are administered to have different onset times, such that the release of each active ingredient of the composition in body can be lag time delayed to a specific rate. Also, the composition is very effective for the treatment of hypertension and the prevention of complications in patients having metabolic syndromes which show diabetes, obesity, hyperlipidemia, coronary artery diseases and the like. More specifically, the composition is a drug delivery system designed such that the release of each drug is controlled to a specific rate, and it can show the most ideal effect, when it is absorbed in body.
