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CONTAINER FOR ADMINISTRATION, STORAGE, DELIVERY OR TRANSPORTATION OF PROTEIN HAVING LOW PROTEIN ADSORBABILITY OR PROTEIN-CONTAINING COMPOSITION, AND APPARATUS FOR PRODUCING PROTEIN OR PROTEIN COMPOSITION
专利权人:
OTSUKA PHARMACEUTICAL FACTORY, INC.;DAIKIN INDUSTRIES, LTD.
发明人:
Kozue KOMAZAWA,Tatsuya HIGUCHI,Koji KIGAWA,Kazuaki OBATA,Takayuki DEMPO,Masuhiro NISHIMURA
申请号:
US16477947
公开号:
US20190365604A1
申请日:
2017.12.21
申请国别(地区):
US
年份:
2019
代理人:
摘要:
There is provided a container or an equipment having low-protein adsorption properties, to be used for administering, storing, conveying or transporting protein or a composition including protein, or for producing protein or a composition including protein. A container or an equipment for producing protein or a composition including protein, wherein the surface of the container or the equipment in contact with protein or a composition including protein is formed of a fluororesin which is at least one fluororesin selected from a tetrafluoroethylene-hexafluoropropylene-based copolymer and a tetrafluoroethylene-perfluoroalkylvinyl ether-based copolymer, which has a melting point of 320° C. or less and which has a total number of non-fluorinated group terminals and —;CF2H group terminals in the fluororesin of 70 or less per 1×106 carbon atoms, has remarkable low-protein adsorption properties. Such a container or equipment can be used to thereby, for example, prevent, in a producing (culturing and purifying, and the like) step, a storing and delivering step and/or administration of a protein formulation such as an antibody pharmaceutical product, the protein formulation from being lost due to adsorption thereof to the equipment.
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来源网址:
http://www.ckcest.cn/home/
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