PROBLEM TO BE SOLVED: To provide a cancer combination therapy using anti-mif antibodies and chemotherapeutics.SOLUTION: The present invention provides a combination therapy for cancer such as pancreatic cancer, ovarian cancer, prostate cancer, breast cancer, and lung cancer, in combination with an anti-MIF (macrophage migration inhibitory factor) antibody and mitoxantrone, doxorubicin and/or cisplatin as a chemotherapeutic agent.SELECTED DRAWING: None【課題】抗MIF抗体と化学療法剤を用いた、癌の併用療法の提供。【解決手段】抗MIF(マクロファージ遊走阻害因子)抗体と化学療法剤としてのミトキサントロン、ドキソルビシン及び/又はシスプラチンを組み合わせた、膵癌、卵巣癌、前立腺癌、乳癌、及び肺癌等の癌治療薬。【選択図】なし