The tree disinfection system using the drone of the present invention can adjust the length and angle of the control hose installed on the drone in parallel with the ground, so that the close-spread and wide-area spraying can be suitably applied to the situation of various terrain trees. have. Accordingly, the wood disinfection system using a drone according to an embodiment of the present invention, a drone, a control unit including a plurality of control hoses are provided at the bottom of the drone and provided with a medicine container and a nozzle at the tip, and the control unit Located in the lower portion is configured to include an angle control unit coupled to the control hose to adjust the spraying angle of the control hose, the drone includes a main body, a plurality of drone arms and a plurality of propellers and drone legs； Rotating cylinder which is located in the lower part of the main body to accommodate the medicine container therein； And a frame coupled to the main body at the top and coupled to the rotary cylinder at the bottom thereof, the frame including a rotating shaft, wherein the control hose is connected to the medicine container and wound on the outer surface of the rotary cylinder. Each branch is connected to the drone arm is configured to include a spray disinfectant through the nozzle, the angle adjustment portion is connected to the frame includes a gas located in the lower portion of the control unit, the gas for storing gas lighter than air, such as helium Tank； A compressor connected to the gas tank to compress, supply, and suck gas； A gas supply pipe connecting the compressor with an arbitrary control hose and forming a passage through which the gas is supplied and sucked by the compressor； A corrugated pipe connected between the control hoses adjacent to the side and connected to the plurality of control hoses and capable of expansion and contraction； And a corrugated pipe fixing unit for coupling the control hose to the compress
