TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
发明人:
PEREZ-LEAL, Oscar
申请号：
WO2017US59816
公开号：
WO2018144087(A3)
申请日:
2017.11.03
申请国别(地区):
世界知识产权组织国际局
年份:
2018
代理人:
摘要：
The present invention provides homologous recombination vectors to insert transgenic DNA in cells. These vectors shorten the production time and allow for easy generation of genetically modified cells. The invention allows the user to test multiple tags and to generate homozygous modified cell line using the homologous recombination vector. The invention can be used to generate knockout cells, to generate cell lines with knockin genes, to generate cell lines for drug screening against any target, to create transgenic animals, or in gene therapy.
