CHATTARAJ SARAT C.,BHAT PAVAN,REDELMAN GLENN A.,WARGO DAVID J.,ADDICKS WILLIAM
申请号：
NZ60296809
公开号：
NZ602968A
申请日:
2009.03.18
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
NZ 602968 The disclosure relates to an extended release pharmaceutical formulation comprising: (a) an extended release portion comprising an active pharmaceutical ingredient (API) and a wax selected from the group consisting of waxes of animal or vegetable origin, synthetic waxes, semi-synthetic waxes, and high-melting pharmaceutically acceptable water-insoluble waxes and (b) an immediate release portion comprising an API in an amount of from 5% w/w to 8% w/w of the immediate release portion said extended and immediate release portions both comprising the same API and wherein the extended release portion comprises a mixture of a free base and a salt of the API in a range of from 1:2 to 2:1.
