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WAYS OF THERAPEUTIC USE OF C-RAF INHIBITOR
专利权人:
НОВАРТИС АГ (CH)
发明人:
КАПОНИГРО Джордано (US),КУК Весселина (US),МАЙС Анна Хелена (CH),НАУВЕЛАЕРТС Хайди (CH)
申请号:
RU2018146886
公开号:
RU2018146886A
申请日:
2017.06.08
申请国别(地区):
RU
年份:
2020
代理人:
摘要:
The present invention relates to the use of a c-Raf inhibitor for use in the treatment of a proliferative disease, particularly a solid tumor that harbors Mitogen-activated protein kinase (MAPK). The present invention also relates to a pharmaceutical combination which comprises (a) at least one antibody molecule (e.g., humanized antibody molecules) that binds to Programmed Death 1 (PD-1), and (b) a c-Raf inhibitor or pharmaceutically acceptable salt thereof. The present invention also relates to such a combination for simultaneous, separate or sequential administration for the treatment of a proliferative disease, particularly a solid tumor that harbors Mitogen-activated protein kinase (MAPK) alteration and a commercial package comprising such a combination.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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