ALAN D. SNOW,GERARDO M. CASTILLO,THOMAS P. LAKE,BETH P. NGUYEN,VIRGINIA J. SANDERS
申请号：
PT11161614
公开号：
PT2380583E
申请日:
2004.12.17
申请国别(地区):
PT
年份:
2013
代理人:
摘要：
A composition of matter that includes at least one of the peptide sequences； Arg-Val-Ala-Val-Ile-Met-Gly-amide (DP-068) and Leu-Ala-Phe-Val-Leu-Arg-Lys-amide (DP-074). A pharmaceutical composition that includes peptides Arg-Val-Ala-Val-Ile-Met-Gly-amide (DP-068) and Leu-Ala-Phe-Val-Leu-Arg-Lys-amide (DP-074). Use of the peptides for preparation of a medicament for the treatment of a diseases characterized by A² fibrillogenesis. Use of an antibody directed against a peptide comprising Leu-Ala-Phe-Val-Leu-Arg-Lys-amide in the manufacture of a medicament for the treatment of a disease characterized by A² fibrillogenesis. Preferably where at least one amino acid of the peptide sequence is a D-amino acid.
