UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEEUNIVERSITY
发明人:
Myung Sook OH,Dong-Hyun KIM,Jin Gyu CHOI
申请号：
US16467350
公开号：
US20200128801A1
申请日:
2017.12.06
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided is an information providing method for diagnosing Parkinson's disease by measuring the amount of any one target selected from the group consisting of a Proteus mirabilis strain, a metabolite produced by the Proteus mirabilis strain, and α-synuclein in a biological sample of a subject； a composition comprising a Proteus mirabilis strain as an active ingredient for fabricating a Parkinson's disease animal model； a method for fabricating a Parkinson's disease animal model, the method comprising a step for administering a Proteus mirabilis strain to an animal excluding human； and a method for screening a Parkinson's disease medicine, the method comprising a step for administering a candidate drug of the Parkinson's disease medicine to the Parkinson's disease animal model and a step for observing the degree of mitigation of Parkinson's disease symptoms to determine the treatment effect of the candidate drug on Parkinson's disease.
