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Coagulation controlling agents and devices comprising the same
专利权人:
Becton, Dickinson and Company
发明人:
Monroe Dougald,Novarra Shabazz,Hoke Randal Alan,Holmes Paul F.,Dudaronek Justyna
申请号:
US201213539846
公开号:
US9949473(B2)
申请日:
2012.07.02
申请国别(地区):
美国
年份:
2018
代理人:
Botos Churchill IP Law LLP
摘要:
A device and kit and method for controlling coagulation in a blood sample. The coagulation controlling agent is at least one of citrate, a protamine salt, its homologs and derivatives, benzamidine, or para-aminobenzamidine. Additives such as water soluble polymers and sugars are also contemplated. The device and kit comprise a container that contains an effective amount of thrombin and a coagulation controlling agent. The method combines thrombin and a coagulation controlling agent to stabilize thrombin or accelerate its activity in a blood sample.
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