An ultrasonic oscillator for manufacturing a collagen matrix comprises a hollow body (10), a receiving groove (20), a transmission component (30), multiple frames (40), multiple oscillation devices (50) and an ultrasonic mechanism (60). The receiving groove (20) is provided in the body (10). The frame (40) is connected to the transmission component (30). The transmission component (30) drives the frame (40) to move away from or to be received in the receiving groove (20). The oscillating devices (50) are respectively connected to the frames (40). The ultrasonic mechanism (60) is arranged in the receiving groove (20). During the process, the oscillating devices (50) and the ultrasonic mechanism (60) act on the connective tissue in the receiving groove (20), so that the connective tissue gradually becomes a collagen matrix.
