Pyrrolopyridinone compounds and HIV treatment procedures

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专利权人:

VIIV Healthcare UK Limited

发明人:

HAYDAR, Simon N.,JOHNS, Brian Alvin,VELTHUISEN, Emile Johann

申请号：

ES12833476

公开号：

ES2632443T3

申请日:

2012.09.18

申请国别(地区):

ES

年份:

2017

代理人:

摘要：

A compound selected from the group consisting of: 2- (1-Benzyl-4- (4-chlorophenyl) -6-methyl-7-oxo-6,7-dihydro-1H-pyrrole [2,3-c] acid pyridin-5-yl) -2- (tert-butoxy) acetic acid, 2- (tert-butoxy) -2- (4- (4-chlorophenyl) -1- (4-fluorobenzyl) -6-methyl-7- oxo-6,7-dihydro-1H-pyrrole [2,3-c] pyridin-5- yl) acetic acid, 2- (tert-butoxy) -2- (4- (4-chlorophenyl) -1- (4 -methoxybenzyl) -6-methyl-7-oxo-6,7-dihydro-1H-pyrrole [2,3-c] pyridin-5- yl) acetic acid, 2- (tert-butoxy) -2- (4- (4-Chlorophenyl) -1- (2-methoxyethyl) -6-methyl-7-oxo-6,7-dihydro-1 H -pyrrole [2,3-c] pyridin-5-yl) acetic acid, 2- ( tert-butoxy) -2- (4- (4-chlorophenyl) -1-isobutyl-6-methyl-7-oxo-6,7-dihydro-1H-pyrrole [2,3-c] pyridin-5-yl) acetic acid (S) -2- (tert-butoxy) -2- (4- (4-chlorophenyl) -1- (3,4-difluorobenzyl) -6-methyl-7-oxo-6,7-dihydro- 1H-pyrrole [2,3-c] pyridin-5- yl) acetic acid, 2- (tert-butoxy) -2- (4- (4-chlorophenyl) -6-methyl-7-oxo-1- (2 - (piperidin-1-yl) ethyl) -6,7-dihydro-1H-pyrrole [2,3-c] pyridin-5- yl) acetic acid, 2- (tert-butoxy) -2- (4- ( 4-chlorophenyl) -6-methyl-7- oxo-1- (2- (piperidin-1-yl) ethyl) -6,7-dihydro-1H-pyrrole [2,3-c] pyridin-5- yl) acetic acid, 2- (tert-butoxy) - 2- (4- (4-Chlorophenyl) -6-methyl-7-oxo-1 - ((5- (trifluoromethyl) furan-2-yl) methyl) -6,7-dihydro-1H-pyrrole [2,3 - c] pyridin-5-yl) acetic acid, 2- (tert-butoxy) -2- (4- (4-chlorophenyl) -1- (imidazo [1,2-a] pyridin-2-ylmethyl) -6 -methyl-7-oxo-6,7-dihydro-1H-pyrrole [2,3- c] pyridin-5-yl) acetic acid, 2- (tert-butoxy) -2- (4- (4-chlorophenyl) -6-methyl-1 - ((2-methylthiazol-4-yl) methyl) -7-oxo-6,7-dihydro-1 H -pyrrole [2,3-c] pyridin-5-yl) acetic acid, 2 acid - (tert-butoxy) -2- (4- (4-chlorophenyl) -1- (2 - ((2-hydroxy-4-methylphenyl) amino) -2-oxoethyl) -6-methyl-7-oxo-6 , 7-dihydro-1H-pyrrol [2,3-c] pyridin-5-yl) acetic acid, 2- (tert-butoxy) -2- (4- (4-chlorophenyl) -6-methyl-7-oxo-1 - (1-Phenylethyl) -6,7-dihydro-1H-pyrrole [2,3-c] pyridin-5-yl) acetic acid, 2- (1-benzyl-3-bromo-4- (4-c

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