The present invention relates to new immunogenic compositions comprising conjugated Streptococcus pneumoniae capsular saccharide antigens (glycoconjugates), kits comprising said immunogenic compositions and uses thereof. Immunogenic compositions of the present invention will typically comprise at least one glycoconjugate from a S. pneumoniae serotype not found in PREVNAR®, SYNFLORIX® and/or PREVNAR 13®. The invention also relates to vaccination of human subjects, in particular infants and elderly, against pneumoccocal infections using said novel immunogenic compositions.本發明關於包含經共軛之肺炎鏈球菌(Streptococcus pneumoniae)莢膜糖抗原(糖共軛物)之新穎致免疫性組成物、包含該致免疫性組成物之套組及彼等之用途。本發明的致免疫性組成物典型上包含至少一種來自未發現於PREVNAR®、SYNFLORIX®及/或PREVNAR 13®的肺炎鏈球菌血清型之糖共軛物。本發明亦關於使用該新穎致免疫性組成物以免疫接種人個體(特別是嬰兒和老人)以對抗肺炎球菌感染。