The invention relates to a storage and mixing device for two-componentpolymethylmethacrylate bone cements, having a cartridge (1) with a cylindrical interior,wherein thecylindrical interior is delimited on a front side by a cartridge head (3), aplunger (2)which is arranged to be axially movable in the cylindrical interior of thecartridge (1) andwhich is spaced from the cartridge head (3), a powdery first parent component(4) of thebone cement, which is contained in the interior between the plunger (2) andthecartridge head (3), a feed-through (5) which is arranged in the cartridge head(3) or inthe cylinder barrel of the cartridge (1) between the plunger (2) and thecartridge head(3), wherein the feed-through (5) is connected to a fluid line (6), areceptacle (16) for amonomer liquid (42), wherein the fluid line (6) connects the feed-through (5)to thereceptacle (16) in a liquid-permeable manner, a press-out device (15) which ispushableinto the receptacle (16), so that monomer liquid (42) is pressable out of thereceptacle(16) into the fluid line (6), wherein the plunger (2) is spaced from a backside of thecylindrical interior, located opposite the front side, so that, by moving theplunger (2) inthe direction of the back side, the press-out device (15) is pushable into thereceptacle(16) and a reduced pressure is producible in the interior of the cartridge (1)between theplunger (2) and the cartridge head (3).The invention also relates to methods for mixing the parent components (4,42).