Mario Pablo Estrada Garcia,Juana Maria Lugo Gonzalez,Yamila Carpio Gonzalez,Carolina Tafalla Pineiro
申请号：
US14839114
公开号：
US09603900B2
申请日:
2015.08.28
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates to the use of pituitary adenylate cyclase activating polypeptide (PACAP) in the treatment of viral diseases and infectious diseases caused by viruses in aquatic organisms. PACAP, alone or combined with an antiviral molecule, demonstrated its effectiveness by increasing the survival of fish or crustaceans infected by viruses when it was administered orally, by injection or by immersion baths. Furthermore, it was observed that treated organisms keep or increase its weight as compared to infected and non-treated organisms. PACAP or PACAP-containing combinations decreased the viral load in tissues and organs susceptible to viral infections as it was determined by RT-PCR.
