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METHOD FOR INACTIVATION OF PATHOGENS IN BLOOD PREPARATIONS, PLASMA OF DONOR BLOOD, BIOLOGICAL PREPARATIONS, AND DEVICE FOR ITS IMPLEMENTATION
专利权人:
Obshchestvo s ogranichennoj otvetstvennostyu "Millisekundnye Tekhnologii" (OOO "MST")
发明人:
Dolgopolov Dmitrij Nikolaevich (RU),Долгополов Дмитрий Николаевич (RU),Sobolev Aleksej Mikhajlovich (RU),Соболев Алексей Михайлович (RU)
申请号:
RU2018127700
公开号:
RU0002696784C1
申请日:
2018.07.27
申请国别(地区):
RU
年份:
2019
代理人:
摘要:
FIELD: pharmaceutics.SUBSTANCE: invention refers to pharmaceutical and / or food industry and aims at reducing the number of pathogens in a liquid. Method for liquid pathogens destruction and / or inactivation involves the following stages: (a) introduction of liquid into the first vessel; (b) introducing an inert gas into a first vessel; (c) increasing pressure in first vessel to first pressure, at which inert gas dissolves in liquid to form liquid-inert gas mixture; (d) heating the liquid-inert gas mixture after exiting from the first vessel to pre-heating temperature; (e) atomising a liquid-inert gas mixture in the form of drops into a second vessel with a second pressure and with a pre-set and maintained during spraying treatment temperature; and (f) cooling the liquid. Said nozzle has inlet and outlet, and first pressure at nozzle inlet is greater than second pressure at nozzle outlet, pre-heating temperature is lower than treatment temperature, pre-heating temperature and processing temperature are selected based on the condition of their minimum difference and to ensure preservation of fluid properties.EFFECT: use of the invention provides higher effectiveness of destruction and / or inactivation of a wide range of infectious agents (pathogens) in liquid, including viruses, without using any chemical reagents, which enables to avoid occurrence of any toxic properties of liquid in connection with use of such reagents, and also allows to completely preserve initial properties of this liquid.29 cl, 3 dwg, 1 tbl, 1 exИзобретение относится к области фармацевтической и/или пищевой промышленности и предназначено для уменьшения количества патогенов в жидкости. Способ уничтожения и/или инактивации патогенов в жидкости включает в себя этапы: (а) введение жидкости в первый сосуд; (b) введение инертного газа в первый сосуд; (c) повышение давления в первом сосуде до первого давления, при котором инертный газ растворяется в жидкости, образуя смесь жидкость–инертный газ; (d
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