Dane Goff,Donald Payan,David Carroll,Simon Shaw,Hitoshi Yasumichi
申请号：
US14376098
公开号：
US09409884B2
申请日:
2013.01.31
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The disclosure relates particularly to certain carboxamide, sulfonamide and amine compounds and pharmaceutical compositions thereof, and to methods of treating and ameliorating disorders and conditions related to the adiponectin pathway, sphingolipid metabolism, oxidative stress, mitochondrial dysfunction, free radical damage and metabolic inefficiency, among others. In certain embodiments, the compounds have the structures (I-1), (2-I) and (3-I)in which the variables are as described herein.
