METHODS FOR TREATING AND/OR PREVENTING GRAFT-VERSUS-HOST DISEASE AND/OR DIFFUSE ALVEOLAR HEMORRHAGE AND/OR VENO-OCCLUSIVE DISEASE ASSOCIATED WITH HEMATOPOIETIC STEM CELL TRANSPLANT

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专利权人:

OMEROS CORPORATION;UNIVERSITY OF LEICESTER

发明人:

DEMOPULOS, Gregory A.,DUDLER, Thomas,SCHWAEBLE, Hans-Wilhelm

申请号：

PH12020500276

公开号：

PH12020500276A1

申请日:

2020.02.06

申请国别(地区):

PH

年份:

2020

代理人:

摘要：

In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a human subject suffering from graft- versus-host disease and/or diffuse alveolar hemorrhage and/or veno-occlusive disease associated with a hematopoietic stem cell transplant. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation.

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中国工程科技知识中心

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http://www.ckcest.cn/home/