Vlieghe, Patrick,David, Marion,Molino, Yves,Khrestchatisky, Michel
申请号:
AU2011244107
公开号:
AU2011244107A1
申请日:
2011.04.18
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The invention relates to peptide derivatives (peptides and pseudo-peptides) and to the use thereof as vectors for molecules of interest. The invention also relates to conjugates containing a peptide derivative of the invention bonded to a molecule of interest. The peptides of the invention can be used for delivering, in the form of conjugates, generally prodrugs, molecules of pharmaceutical or diagnostic interest, for instance therapeutic molecules, imaging or diagnostic agents or molecular probes, across cell membranes, and in particular for promoting transport thereof across the blood-brain barrier (BBB).