A use of a bioresorbable hemostatic device at a site of bleeding in the bodyof apatient for assisting hemostasis is provided. The bioresorbable hemostaticdevice comprises awafer comprising a compressed, particularized, dehydrated extracellular matrixmaterial(ECM) derived from an epithelial tissue comprising hemostatic properties andcomponents ofECM isolated in their native configuration, said ECM further comprisingepithelial basementmembrane and consisting of one or more layers of said epithelial tissue, and,a backingcomprising a devitalized extracellular matrix material, said backing joined tosaid wafer and,said bioresorbable hemostatic device is for substantially arresting blood flowat said site ofbleeding at a rate that exceeds arresting blood flow in the absence of ahemostatic device atsaid site of bleeding.
