A hydrogen production device includes a reaction unit and a hydrogen collection unit. The reaction unit includes a first region, a second region and a barrier layer. The first region stores a solid-state reactant, the second region stores a liquid-state reactant, and the barrier layer separates the first region from the second region. When the barrier layer forms an opening, the solid-state reactant comes into contact and reacts with the liquid-state reactant to produce hydrogen gas. The hydrogen collection unit has at least one gas vent to lead the hydrogen gas to flow into a hydrogen acceptor via the gas vent. The hydrogen gas is allowed to flow through the hydrogen collection unit, and the liquid-state reactant is prevented from entering the hydrogen collection unit.
