A pressure sensing unit and a human body acupressure structure by applying the same are described. The pressure sensing unit includes an external casing, a button, a resilient element and a switch. The external casing has a space and includes a first end part and a second end part located respectively on two opposite ends of the external casing. The first end part and the second end part are set with a first opening and a second opening respectively. The button is disposed inside the space and one end of the button protrudes outside the first opening. The resilient element is disposed inside the space and includes a first end and a second end opposite to each other. The first end is against a bottom of the button, and the second end is against the second end part of the external casing. The switch includes a press button and a conductive part. The press button includes a third part and a forth part opposite to each other. The third part is located near the bottom of the button. The forth part passes through the second opening of the external casing. The conductive part connects to the forth part and includes two electric connection elements.一種壓力感應單元及其所應用之人體穴道按摩結構。壓力感應單元包含外殼體、按壓鈕、彈性元件及開關。外殼體具有容置空間且包含分別位於外殼體之相對二端的第一與第二端部。第一與第二端部分別設有第一與第二開口。按壓鈕設置於容置空間中,按壓鈕一端突出於第一開口外。彈性元件設於容置空間中,且具有相對之第一與第二端。第一端抵住按壓鈕底部,第二端抵住外殼體之第二端部。開關包含按鈕及導電部,按鈕具有相對之第三與第四部。第三部鄰近於按壓鈕之底部,第四部穿設於外殼體之第二開口中。導電部與第四部接合,並包含二電氣連接組件。100‧‧‧壓力感應單元110‧‧‧外殼體111‧‧‧容置空間112‧‧‧第一端部113‧‧‧第二端部114‧‧‧第一開口115‧‧‧第二開口116‧‧‧內螺紋120‧‧‧按壓鈕121‧‧‧底部130‧‧‧彈性元件131‧‧‧第一端132‧‧‧第二端140‧‧‧按鈕141‧‧‧第三部142‧‧‧第四部143‧‧‧外螺紋150‧‧‧導電部151‧‧‧電氣連接組件160‧‧‧開關170‧‧‧間隙180‧‧‧螺帽
