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DERIVE D'ACIDE QUINOLONECARBOXYLIQUE 7-(4-SUBSTITUE 3-CYCLOPROPYLAMINOMETHYL-1-PYRROLIDINYLE)
专利权人:
KYORIN PHARMACEUTICAL CO.; LTD.
发明人:
ASAHINA, YOSHIKAZU,TAKEI, MASAYA
申请号:
CA2536429
公开号:
CA2536429C
申请日:
2004.09.08
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
[PROBLEMS] To provide a novel quinolonecarboxylic acid compound which is safe,has potent antibacterial activity, and is effective against resistant bacteriawhich are less controlled by conventional antibacterials. [MEANS FOR SOLVINGPROBLEMS] It is a 7-(4-substituted 3-cyclopropylaminomethylpyrrolidinyl)quinolonecarboxylic acid derivativerepresented by the general formula (I)(typical example: 1-cyclopropyl-7-[(3S,4S)-3-cyclopropyl~aminomethyl-4-fluoro-1-pyrrolidinyl]-6-fluoro-1,4-dihydro~8-methoxy-4-oxo-3-quinolinecarboxylic acid). The derivative has potentantibacterial activity against gram-positive bacteria, in particular,resistant bacteria such as MRSA, PRSP, and VRE, and is highly safe.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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