An airtight interlocking type negative pressure snore-ceasing equipment including an upper jaw tooth socket, and lower jaw tooth socket, and connecting piece is provided. The upper jaw tooth socket has a first opening and a first space. The first space is communicated with the first opening. The lower jaw tooth socket has a second opening and a second space. The second space is communicated with the second opening. The connecting piece is disposed between the upper jaw tooth socket and the lower jaw tooth socket to separate the first space and the second space. The connecting piece has a guiding passage formed between the upper jaw tooth socket and the lower jaw tooth socket.一種全氣密咬合式負壓止鼾器包括一上顎牙套、一下顎牙套以及一連接件。上顎牙套具有第一開口及第一空間。第一空間連通第一開口。下顎牙套具有第二開口及第二空間。第二開口連通第二空間，第二空間連通第二開口。連接件配置在上顎牙套與下顎牙套之間，以分隔第一空間與第二空間，且連接件具有一導引通道，形成在上顎牙套與下顎牙套之間。
