A dispense interface for use with a drug delivery device with an inner body and with a lockout element. The lockout element is coupled to the inner body movable from a receptive condition to a locked condition, wherein in the receptive condition the dispense interface is attachable to the drug delivery device. In the locked condition, the dispense interface is not-attachable to the drug delivery device. The lockout element is configured to move from the receptive condition to the locked condition when said dispense interface is attached to and detached from said drug delivery device.