Certain example embodiments of this invention relate to systems and/or methods for stimulating the brain, e.g., to promote learning and/or memory, to provide therapeutic treatments thereto, etc. In certain example embodiments, neurons are monitored and their activities are analyzed to determine the electrical and electrochemical pathways that are activated during specific learning functions, events, etc. Given an established mapping, certain example embodiments deliver electrical and electrochemical signals to specifically targeted brain locations in order to facilitate learning and/or memory, to provide therapeutic treatments thereto, etc. For example, neurons or gateways thereto may be stimulated to facilitate learning, memory and/or recall, to counteract or mitigate the onset or arrival of mental or neurological diseases and disorders, etc.