Methods of associating genetic variants with a clinical outcome in patients suffering from age-related macular degeneration treated with anti-vegf

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专利权人:

REGENERON PHARMACEUTICALS INC.

发明人:

Perlee, Lorah,Hamon, Sara

申请号：

NZ74402516

公开号：

NZ744025A

申请日:

2016.12.01

申请国别(地区):

NZ

年份:

2020

代理人:

摘要：

Methods for associating a genetic variant with intraretinal fluid as a marker for response to therapy with anti-VEGF in age-related macular degeneration (AMD). Disclosed herein are further methods for associating a genetic variant with visual acuity, anatomic outcomes or treatment frequency. The genetic variants identified are found in a gene-free region on chromosome X p.22.3, in the MECOM gene, in the NTRK3 gene and in the ANK2 gene.

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中国工程科技知识中心

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