An X-ray diagnosis apparatus includes: a reference value calculating unit that calculates a reference value used for normalizing a flow of a contrast material, on the basis of a chronological transition of a signal intensity of the contrast material in a predetermined region, for each of a plurality of groups of X-ray images chronologically taken while using the contrast material; an index image generating unit that normalizes, for each of the plurality of groups of X-ray images, the flow of the contrast material at each of pixels by using the reference value calculated by the reference value calculating unit and that generates an image in which a feature value of the normalized flow of the contrast material is reflected in each of the pixels; and a displayed image calculating unit that causes a predetermined display unit to display the image generated by the index image generating unit.