An earphone comprises an earphone body, containing a speaker, and a projection, extending from a first surface of the earphone body, for location in the entrance to the users ear canal. The earphone body comprises a sound outlet in the first surface, for allowing sounds generated by the speaker to leave the earphone body. The projection extends from the first surface of the earphone body, adjacent to the sound outlet, and contains a sound inlet port, connected to a microphone for detecting sounds entering the ear canal. A noise cancellation system includes noise cancellation circuitry, for applying a frequency dependent filter characteristic and applying a gain to an input signal representing ambient noise, at least one of the frequency dependent filter characteristic and the gain being adaptive. The earphone then has an ambient noise microphone, and an error microphone connected to the sound inlet port.