IM DAE SEONG,SHIN JAE HEE,PARK YOUNG JIN,SONG DAE HAE,BAE SUNG MIN,KWON SE CHANG
申请号：
NZ60305011
公开号：
NZ603050A
申请日:
2011.04.04
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
NZ 603050 Disclosed is an insulin conjugate prepared by linking insulin with an immunoglobulin Fc region via a non-peptidyl polymer selected from the group consisting of polyethylene glycol, polypropylene glycol, copolymers of ethylene glycol and propylene glycol, polyoxyethylated polyols, polyvinyl alcohol, polysaccharides, dextran, polyvinyl ethyl ether, biodegradable polymers, lipid polymers, chitins, hyaluronic acid, and combinations thereof, in which the non-peptidyl polymer is linked to the amino terminal of beta chain of insulin.
