CHAPPIE, THOMAS ALLEN,VERHOEST, PATRICK ROBERT,PATEL, NANDINI CHATURBHAI,HAYWARD, MATTHEW MERRILL,HELAL, CHRISTOPHER JOHN,SCIABOLA, SIMONE,WAGER, TRAVIS T.,LACHAPELLE, ERIK ALPHIE,YOUNG, JOSEPH MICHAE
申请号:
CA2897843
公开号:
CA2897843C
申请日:
2015.07.21
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention is directed to compounds of Formula I: (see formula I) or a pharmaceutically acceptable salt thereof, wherein the substituents A, R1, R3, and b are as defined herein. The inventions also directed to pharmaceutical compositions comprising the compounds, uses of the compounds as inhibitors of PDE4 isozymes and methods of preparing the compounds.