abstract disclosed are synthetic nanocarrier methods, and related compositions, including b cell and / or mhc class ii-restricted epitopes and immunosuppressants in order to generate tolerogenic immune responses, such as the generation of antigen-specific regulatory b cells. Abstract of the Summary Patents: "Tolerogenic Synthetic Nanocarriers for Regulatory B-Cell Induction". Synthetic nanotransport methods, and related compositions, comprising mhc class II restricted b-cells and / or epitopes and immunosuppressants are disclosed in order to generate tolerogenic immune responses, such as generation of antigen-specific regulatory b-cells.abstract disclosed are synthetic nanocarrier methods, and related compositions, comprising b cell and/or mhc class ii-restricted epitopes and immunosuppressants in order to generate tolerogenic immune responses, such as the generation of antigen-specific regulatory b cells. tradução do resumo resumo patente de invenção: "nanotransportadores sintéticos tolerogênicos para indução de células b reguladoras". são divulgados métodos de nanotransportadores sintéticos, e composições relacionadas, compreendendo células b e/ou epítopos restritos a mhc de classe ii e imunossupressores de modo a gerar respostas imunes tolerogênicas, tais como a geração de células b reguladoras específicas de antigênio.
