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LIQUID BIOLOGICAL ANTI-FUNGAL DRUG CONTAINING THE PYTHIUM OLIGANDRUM MICRO-ORGANISM AND METHOD FOR PRODUCING IT
专利权人:
БИОПРЕПАРАТЫ, СПОЛ. С Р.О.
发明人:
Мартин,Ян,Томаш,Адам
申请号:
EA201990201
公开号:
EA201990201A1
申请日:
2017.10.16
申请国别(地区):
EA
年份:
2019
代理人:
摘要:
A liquid biological antifungal preparation containing the microorganism Pythium oligandrum, comprising a stabilized suspension of the microorganism Pythium oligandrum, containing 0.05-10.0 wt.% Cultured biomass of the microorganism Pythium oligandrum, including the culture medium, cell forms of the specified microorganism and substances produced by the specified microorganism, and 90.0-99.95 wt.% Stabilizer, with a predetermined number of dormant oospores in 1 ml of the specified liquid biological antifungal drug after standard but formalization ranges from 1 × 10 to 2 × 10. The liquid biological antifungal preparation contains the microorganism Pythium oligandrum, including a stabilized suspension of the microorganism Pythium oligandrum, 0.05-10.0 wt.% Cultured biomass of the microorganism Pythium oligandrum, including the cultivation medium, cell forms of the specified microorganism and substances produced by the specified microorganism, and 79, 77-99.95 wt.% Stabilizer, with the rest containing up to 100 wt.% At least one modifier / excipient selected from the group comprising a filler, aroma op and vitamin; wherein a predetermined number of dormant oospores in 1 ml of the indicated liquid biological antifungal drug after standard normalization is in the range from 2.5 × 10 to 1.0 × 10. The microorganism Pythium oligandrum is a strain of Pythium oligandrum Dreschler ATTC 38472 deposited in the Czech Microorganism Collection (CCM) at the Masaryk University in Brno under the name Pythium oligandrum M1. The stabilizer may be water, saline, oil, or a concentrated solution of osmolytes. The method of obtaining the specified liquid biological antifungal drug.Жидкий биологический противогрибковый препарат, содержащий микроорганизм Pythium oligandrum, включающий стабилизированную суспензию микроорганизма Pythium oligandrum, содержащую 0,05-10,0 вес.% культивированной биомассы микроорганизма Pythium oligandrum, включающей среду культивирования, клеточные формы указанного
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