SUSANNE U. MERTENS-TALCOTT;ARIELA BETSY THOMAS;VINICIUS DE PAULA VENANCIO;GEOFFREY R. PFEIFER;BLAKE M. EBERSOLE
发明人:
SUSANNE U. MERTENS-TALCOTT,ARIELA BETSY THOMAS,VINICIUS DE PAULA VENANCIO,GEOFFREY R. PFEIFER,BLAKE M. EBERSOLE
申请号：
US16442075
公开号：
US20190380988A1
申请日:
2019.06.14
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Pharmaceutical or nutraceutical formulations are provided for treating inflammation in a subject in need thereof, as well as methods of treating inflammation in a subject in need thereof by administering one of the formulations. In some aspects, the pharmaceutical or nutraceutical formulation includes an effective amount of (i) palmitoylethanolamide or a derivative thereof, and (ii) one, two, three or more different small-molecule polyphenols or derivatives thereof to alleviate one or more causes or symptoms of the inflammation in the subject. In some aspects, the formulations include all three, e.g. the formulations includes (i) palmitoylethanolamide or a derivative thereof, (ii) quercetin or a derivative thereof, and (iii) curcumin or a derivative thereof. In some instances, the components (i)-(iii) discussed above are present at a mass ratio of about (i) 4 mg to 6 mg of palmitoylethanolamide or a derivative thereof to (ii) about 0.5 to 2.5 mg curcumin or a derivative thereof, and (iii) about 0.5 mg to 1.5 mg quercetin or a derivative thereof.
