THE INSTITUTE OF BIOPHYSICS CHINESE ACADEMY OF SCIENCES
发明人:
LIU, YINGFANG,HE, XIAOJING,ZENG, ZONGHAO,ZHOU, JIE
申请号:
EP09712540
公开号:
EP2277891A4
申请日:
2009.02.22
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
Provided are the expression method of influenza virus polymerase PAc-PB1N N complex, the co-crystallization method of the complex and the three-dimendional structure of the crystal of PAc-PB1N complex. Also provided are the compounds binding to the influenza virus polymerase PAc and the expression method of influenza virus polymerase PAN. The three-dimensional structure of the crystal of PAc-PB1N complex can be used for screening and designing the drug for the treatment of influenza.