The present invention relates to the use of avocado skin for obtaining an avocado unsaponifiable material enriched with saturated aliphatic hydrocarbons and with sterols, wherein said avocado skin represents 5% to 50% by weight relative to the total weight of avocados used. The invention also relates to a process for obtaining an avocado unsaponifiable material enriched with saturated aliphatic hydrocarbons and with sterols from at least avocado skin, wherein said avocado skin represents 5% to 50% by weight relative to the total weight of avocados used. The invention also relates to an avocado unsaponifiable material enriched with saturated aliphatic hydrocarbons and with sterols, which can be obtained by means of this process. Finally, the invention relates to an avocado unsaponifiable material enriched with saturated aliphatic hydrocarbons and with sterols, for use as a medicament, advantageously in the prevention and/or treatment of connective tissue disorders such as arthrosis, pathological joint conditions such as rheumatism, or else periodontal diseases, such as gingivitis or periodontitis.