SATO TETSUYA,사토 데츠야,MINOWA TAKUYA,미노와 다쿠야,HOSHIKA YUSUKE,호시카 유스케,TOYOFUKU HIDEKAZU,도요후쿠 히데카즈
申请号：
KR1020147032097
公开号：
KR1020150003336A
申请日:
2013.04.23
申请国别(地区):
KR
年份:
2015
代理人:
摘要：
An object of the present invention is to provide a sustained-release injectable preparation which is in a medication administration form that can provide the effect of 7-[4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one for a prolonged period of time, the preparation releasing a therapeutically effective amount of 7-[4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one for at least one week. The present invention provides an injectable preparation containing 7-[4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one or a salt thereof as an active ingredient, which releases the active ingredient in such a manner that its blood concentration is maintained for at least one week.본 발명은 7-[4-(4-벤조[b]티오펜-4-일-피페라진-1-일)부톡시]-1H-퀴놀린-2-온의 장시간 작용을 갖는 약물 투여 형태로서, 적어도 1 주간, 유효 치료량으로 7-[4-(4-벤조[b]티오펜-4-일-피페라진-1-일)부톡시]-1H-퀴놀린-2-온을 방출하는 지속성 주사 제제를 제공하는 것을 과제로 한다. 본 발명에 의해, 7-[4-(4-벤조[b]티오펜-4-일-피페라진-1-일)부톡시]-1H-퀴놀린-2-온 또는 그 염을 유효 성분으로서 함유하는, 혈중 농도가 적어도 1 주간 이상 지속되는 주사 제제가 제공된다.
