KOBAYASHI, MAMORU,TOMIYAMA, YOSHITAKA,KOBAYASHI, KUMI
申请号：
HK09104243.8
公开号：
HK1125634B
申请日:
2009.05.08
申请国别(地区):
HK
年份:
2012
代理人:
摘要：
The present invention provides pharmaceutical compositions useful for relieving pain caused by ureteral calculi, facilitating exclusion of ureteral calculi or the like. That is, the present invention provides a pharmaceutical composition for the treatment of ureteral lithiasis, which comprises as an active ingredient an indoline derivative represented by the following general formula (I) or a salt thereof. In the formula, R represents saturated or unsaturated aliphatic acyl which may have a substituent； hydroxyalkyl； aliphatic acyloxyalkyl； lower alkyl which has as a substituent lower alkoxy, carboxy, lower alkoxycarbonyl, aryl-substituted lower alkoxycarbonyl, carbamoyl, mono or di(lower alkyl)-substituted carbamoyl or cyano； optionally substituted aromatic acyl； furoyl or pyridylcarbonyl； R 1 represents cyano or carbamoyl； and R 2 represents lower alkyl which may have as a substituent halogen, cyano or aryl.
