Systems and methods are described for communicating the distress or pain experienced by an infant or a non-communicative patient. The systems and methods can provide an objective quantification of pain and/or distress in conjunction with, e.g., various distressing procedures commonly found in the newborn intensive care unit (NICU). The systems may include a processor in communication with a distress level input device and a display configured to provide a representation of a pain or distress score calculated in the processor. The processor may include executable code to translate data from the distress level input into the distress score.