PREPARATION A GRANDE ECHELLE D'AMINOGLYCOSIDES DE PSEUDO-TRISACCHARIDES ET D'INTERMEDIAIRES DE CEUX-CI

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专利权人:

ELOXX PHARMACEUTICALS LTD.

发明人:

MIZHIRITSKII, MICHAEL,KOTALA, MANI BUSHAN,PALIDI, RAVINDER

申请号：

CA3055883

公开号：

CA3055883A1

申请日:

2018.03.15

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

Synthetic pathways for preparing pseudo-trisaccharide aminoglycoside compounds represented by Formula I or Ia as defined in the specification and donor and acceptor compounds useful for preparing such compounds are provided. A process of stereoselectively preparing compounds represented by Formula III as defined in the specification, while avoiding chromatographic separation of stereoisomers are also provided. Compounds prepared by the described processes and uses thereof are also provided.

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