Provided in the present invention is an oseltamivir granule containing oseltamivir or a pharmaceutically acceptable salt, and a pharmaceutically acceptable additive, having average particle size of 150-400 &mum, and including 15-35 wt% of particles of 500-850 &mum. Provided are a capsule comprising the granule, and a method for manufacturing the capsule. Provided is the oseltamivir granule improving productivity of a capsule by having excellent fluidity compared with an existing granule used in an oseltamivir capsule, and not only having bioavailability level similar to an existing oseltamivir when formulated into a capsule, but also improving stability of an oseltamivir free-base.COPYRIGHT KIPO 2016본 발명은 오셀타미비어 또는 약제학적으로 허용 가능한 그의 염, 및 약제학적으로 허용 가능한 첨가제를 함유하는 과립으로서, 상기 과립은 평균입도가 150-400 ㎛이고, 500 ㎛ 내지 850 ㎛의 입자를 15 내지 35 중량% 포함하는 것인 오셀타미비어 과립, 그 과립을 포함하는 캡슐제, 그 캡슐제의 제조방법을 제공한다.
