Heinz W. Gschwend;Shaoyi Sun;Nagasree Chakka;Shifeng Liu;Mikhail A. Kondratenko;Melwyn Abreo;Wenbao Li;Serguei Sviridov;Daniel F. Harvey;Vishnumurthy Kodumuru;Rajender Kamboj;Michael D. Winther
发明人:
Melwyn Abreo,Daniel F. Harvey,Mikhail A. Kondratenko,Wenbao Li,Rajender Kamboj,Vishnumurthy Kodumuru,Michael D. Winther,Heinz W. Gschwend,Nagasree Chakka,Shifeng Liu,Serguei Sviridov,Shaoyi Sun
申请号:
US12816076
公开号:
US08383628B2
申请日:
2010.06.15
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I):wherein W, V, x, y, R1, R2, R3, R4, R5, R6, R7, R7a, R8, R8a, R9, R9a, R10 and R10a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.