Robert L. Hudkins;Sankar Chatterjee;Derek D. Dunn;James L. Diebold;Allison L. Zulli;Reddeppa reddy Dandu;Gregory J. Wells
发明人:
Sankar Chatterjee,Reddeppa reddy Dandu,James L. Diebold,Derek D. Dunn,Robert L. Hudkins,Gregory J. Wells,Allison L. Zulli
申请号:
US12949254
公开号:
US08716493B2
申请日:
2010.11.18
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention is directed to novel multicyclic molecules that mediate enzymatic activity. In particular, the compounds may be effective in the treatment of diseases or disease states related to the activity of PARP, VEGFR2, and MLK3 enzymes, including, for example, neurodegenerative diseases, inflammation, ischemia, and cancer.