University of Southern California;The Regents of the University of California
发明人:
EMERSON, Jane F.
申请号：
EP16769195
公开号：
EP3247419A4
申请日:
2016.01.22
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
Compositions and methods for separating a sample of whole blood or bone marrow aspirate into a fraction rich in at least one of platelets and pluripotent cells are provided. A sample of whole blood can be centrifuged in a collection tube comprising a separator substance formulated to settle between the PRP fraction and the at least one other fraction. Preferably, centrifugation is completed without substantial activation of platelets. Optionally, the separator substance could be hardened to form a solid barrier that allows removal of all or substantially all of the platelets in the PRP fraction without remixing of the PRP fraction with the at least one other fraction. Transfer devices and methods are also provided in which a sterile sample can be transferred from a separation/preparation container (e.g., vacutainer) to a consumer or other container (e.g., dropper) while maintaining sterility of the sample.
