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Artificial tissue constructs comprising alveolar cells and methods for using the same
专利权人:
发明人:
Ayesha Mahmood,Anatoly Kachurin,William Warren,Russell Higbee
申请号:
US14153535
公开号:
US09566250B2
申请日:
2014.01.13
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention comprises artificial tissue constructs that serve as in vitro models of mammalian lung tissue. The artificial tissue constructs of the present invention comprise functionally equivalent in vitro tissue scaffolds that enable immunophysiological function of the lung. The constructs can serve as novel platforms for the study of lung diseases (e.g., interstitial lung diseases, fibrosis, influenza, RSV) as well as smoke- and smoking-related diseases. The artificial tissue constructs of the present invention comprise the two components of alveolar tissue, epithelial and endothelial cell layers.
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