Mitchell Wortzman,R. Todd Plott,Steven B. Newhard,David Watt
申请号：
US12861424
公开号：
US08722650B1
申请日:
2010.08.23
申请国别(地区):
US
年份:
2014
代理人:
摘要：
An oral dosage form has the following: an amount of minocycline selected from the group consisting of 55 mg, 80 mg, and 105 mg an amount of lactose monohydrate an amount of hydroxypropylmethylcellulose. The hydroxypropylmethylcellulose is at least 8.3 to about 9.8% hydroxypropoxylated. The minocycline in the oral dosage form has a dissolution profile or release rates about 35% to about 50% in 1 hour, about 60% to about 75% in 2 hours, and at least about 90% in 4 hours. There is also provided a method of treating acne in a human and a method of assisting a physician in prescribing a dose of minocycline for the treatment of acne.
