Jan Grimm,Fabrice Heitz,Feng Chen,Ioana Combaluzier
申请号:
US15258883
公开号:
US10072074B2
申请日:
2016.09.07
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided are novel human islet amyloid polypeptide, also known as amylin and IAPP and proIAPP respectively, specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for IAPP and/or proIAPP are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for IAPP and/or proIAPP targeted immunotherapy and diagnostics, respectively.