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THERAPEUTIC VACCINES FOR TREATING HERPES SIMPLEX VIRUS TYPE 2 INFECTIONS
专利权人:
Biomedical Research Models; Inc.
发明人:
Yang, Kejian,Guberski, Dennis L.
申请号:
AU2018236682
公开号:
AU2018236682A1
申请日:
2018.09.24
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
#$%^&*AU2018236682A120181011.pdf#####Abstract The invention provides methods and kits for inducing a therapeutic immunity in animals (e.g. mammals) against viral antigens, including herpes-simplex virus type 2. In particular, the invention provides a method of treating animals with an established HSV-2 infection by administering a therapeutic vaccine comprising a priming dose of a nucleic acid encoding an HSV-2 antigen, an initial or first boosting dose comprising the protein form of the antigen encapsulated in liposomes, and one or more subsequent boosting doses comprising both the nucleic acid encoding the HSV-2 antigen and the liposomal-encapsulated protein antigen. See Fig. 7.WO 2014/107731 PCT/US2014/010516 7 -H H -H 'CIA A JJ11 0 Ac E c-1Wc
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