A signal indicative of left atrial pressure in the heart of a patient is analyzed to identify a signal component that is related to the respiration of the patient. An indication relating to the left atrial pressure may be generated based on the presence, absence, or magnitude of the respiratory component. In some embodiments the indication may be used to indicate high left atrial pressure. In some embodiments the indication may be used to indicate heart failure. In some embodiments the indication may be used in conjunction with verifying the operation of a left atrial pressure sensor. In the event of high left atrial pressure or an incorrect pressure reading an appropriate warning may be generated. In the event of an incorrect pressure reading the left atrial pressure sensor may be recalibrated.